The NLRP7 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NLRP7. This antibody recognizes Human, Mouse, and Rat antigen. The NLRP7 Polyclonal Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Immunohistochemistry.
Description
This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms